Mycotoxin management in agriculture is an essential challenge for maintaining the health of both animals and humans. Choosing the right adsorbent is still a question for many breeders and an important criterion for feed manufacturers. New adsorbents are still being sought. Graphene oxide is a promising material in the field of nanotechnology, which excels in its adsorption properties. Presented in vitro study investigates graphene oxide for the binding of mycotoxins from crushed wheat. The results show that graphene oxide has an adsorption capacity for aflatoxin 0.045 mg/g, zearalenone 0.53 mg/g and deoxynivalenol 1.69 mg/g at 37° C. In vitro simulation of crushed wheat digestion showed rapid adsorption during the gastric phase. Of the minerals, Mg, Cu and Zn were the most adsorbed. The applied dose of graphene oxide of 10 mg/g caused only a slight inhibition of the digestive enzymes α-amylase and trypsin compared to pepsin and gastric lipase. In vitro results indicated the suitability of graphene oxide in the adsorption of the aflatoxin, zearalenone and deoxynivalenol.

农业中的霉菌毒素管理是维持动物和人类健康的一项重要挑战。对于许多育种者来说，选择正确的吸附剂仍然是一个问题，也是饲料生产商的重要标准。仍在寻找新的吸附剂。氧化石墨烯是纳米技术领域中一种有前途的材料，其吸附性能优异。提出的体外研究调查了氧化石墨烯与碎麦中霉菌毒素的结合。结果表明，氧化石墨烯在37°C时对黄曲霉毒素0.045 mg / g，玉米赤霉烯酮0.53 mg / g和脱氧雪茄烯醇1.69 mg / g的吸附能力。碎小麦消化的体外模拟显示在胃相中快速吸附。在矿物中，Mg，Cu和Zn吸附最多。与胃蛋白酶和胃脂肪酶相比，所施加的氧化石墨烯剂量为10 mg / g时，对消化酶α-淀粉酶和胰蛋白酶的抑制作用很小。体外结果表明氧化石墨烯适合吸附黄曲霉毒素，玉米赤霉烯酮和脱氧雪腐烯醇。