Liquid‐phase adsorption has hardly been established in micro‐flow, although this constitutes an industrially vital method for product separation. A micro‐flow UV‐photo isomerization process converts cis‐cyclooctene partly into trans‐cyclooctene, leaving an isomeric mixture. Trans‐cyclooctene adsorption and thus separation was achieved in a fixed‐bed micro‐flow reactor, packed with AgNO₃/SiO₂ powder, while the cis‐isomer stays in the flow. The closed‐loop recycling‐flow has been presented as systemic approach to enrich the trans‐cyclooctene from its cis‐isomer. In‐flow adsorption in recycling‐mode has hardly been reported so that a full theoretical study has been conducted. This insight is used to evaluate three process design options to reach an optimum yield of trans‐cyclooctene. These differ firstly in the variation of the individual residence times in the reactor and separator, the additional process option of refreshing the adsorption column under use, and the periodicity of the recycle flow.

中文翻译：

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顺式环辛烯光异构化为反式环辛烯：集成微流反应器和特异性吸附分离

液相吸附在微流中几乎尚未建立，尽管这构成了工业上重要的产品分离方法。微流紫外光异构化过程将顺式环辛烯部分转化为反式环辛烯，留下异构体混合物。反式环辛烯的吸附和分离是在装有AgNO ₃ /SiO ₂粉末的固定床微流反应器中实现的，而顺式异构体则留在流动中。闭环循环流程已被提出作为从顺式异构体中富集反式环辛烯的系统方法。循环模式的流动吸附几乎没有报道，因此已经进行了完整的理论研究。这一见解用于评估三种工艺设计方案，以达到反式环辛烯的最佳产率。它们的不同之处首先在于反应器和分离器中各自停留时间的变化、更新使用中的吸附塔的附加工艺选项以及再循环流的周期性。