Cellular senescence is a state of permanent cell cycle arrest accompanied by unique secretory actions, which influences tissue formation, tumor suppression and aging in vivo. Recent evidences suggest that metabolic and epigenomic reprogram cooperatively creates phenotypic differences of senescent cells, which may provide new clues to control aging processes.

中文翻译：

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代谢和表观基因组重塑引起的细胞衰老变异。

细胞衰老是一种永久性细胞周期停滞状态，伴随着独特的分泌作用，影响组织形成、肿瘤抑制和体内衰老。最近的证据表明，代谢和表观基因组重编程共同创造了衰老细胞的表型差异，这可能为控制衰老过程提供新的线索。