当前位置: X-MOL 学术Chem. Heterocycl. Comp. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
An efficient method for accessing carboannulated and functionalized [1,2,3]triazolo[4,5- b ]pyridines
Chemistry of Heterocyclic Compounds ( IF 1.4 ) Pub Date : 2020-09-23 , DOI: 10.1007/s10593-020-02771-9
Natalia А. Syrota , Sergiy V. Kemskiy , Andriy V. Bol’but , Igor I. Chernobaev , Mikhailo V. Vovk

4-(N-Boc-amino)-1,2,3-triazole-5-carbaldehydes upon heating under reflux in acetic acid in the presence of pyrrolidine react with cycloalkanones, acetylacetone, 1,3-cyclohexanediones, and malononitrile resulting in annulation of the pyridine ring with the formation of new derivatives of [1,2,3]triazolo[4,5-b]pyridine.



中文翻译:

一种获得碳环化和官能化的[1,2,3]三唑[4,5-b]吡啶的有效方法

在吡咯烷存在下在乙酸中加热回流加热后,4-(N -Boc-氨基)-1,2,3-三唑-5-甲醛与环烷酮,乙酰丙酮,1,3-环己烷二酮和丙二腈反应,导致环化反应吡啶环上形成[1,2,3]三唑并[4,5- b ]吡啶的新衍生物。

更新日期:2020-09-23
down
wechat
bug