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Adipose-derived mesenchymal stem cell seeded Atelocollagen scaffolds for cardiac tissue engineering.
Journal of Materials Science: Materials in Medicine ( IF 4.2 ) Pub Date : 2020-09-23 , DOI: 10.1007/s10856-020-06425-2 Qiong Li 1 , Miaomiao Li 2 , Meng Li 1 , Zhengyan Zhang 3 , Han Ma 1 , Liang Zhao 4 , Min Zhang 5 , Guodong Wang 1
中文翻译：
脂肪来源的间充质干细胞接种端端肽胶原支架用于心脏组织工程。
更新日期：2020-09-23
Journal of Materials Science: Materials in Medicine ( IF 4.2 ) Pub Date : 2020-09-23 , DOI: 10.1007/s10856-020-06425-2 Qiong Li 1 , Miaomiao Li 2 , Meng Li 1 , Zhengyan Zhang 3 , Han Ma 1 , Liang Zhao 4 , Min Zhang 5 , Guodong Wang 1
Affiliation
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ADMSCs were isolated from subcutaneous adipose tissue, characterized and cultured in vitro. GFP-labeled ADMSCs can grow and proliferate well on the Atelocollagen scaffolds, and induced by 5-aza the cells can differentiate into cardio-like cells. 3D cultured ADMSCs on Atelocollagen scaffolds were transplanted into mice ischemia myocardium, and have good biocompatibility with host cardio tissue.
中文翻译：
脂肪来源的间充质干细胞接种端端肽胶原支架用于心脏组织工程。
ADMSCs 从皮下脂肪组织中分离出来，在体外进行表征和培养。GFP 标记的 ADMSCs 可以在 Atelocollagen 支架上很好地生长和增殖，并且在 5-aza 的诱导下，细胞可以分化为心脏样细胞。Atelocollagen 支架上 3D 培养的 ADMSCs 被移植到小鼠缺血心肌中，与宿主心脏组织具有良好的生物相容性。
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