当前位置: X-MOL 学术Cardiovasc. Ther. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Analysis of Clinical Efficacy of Traditional Chinese Medicine in Recovery Stage of Stroke: A Systematic Review and Meta-Analysis
Cardiovascular Therapeutics ( IF 3.4 ) Pub Date : 2020-09-22 , DOI: 10.1155/2020/7172052
Xue Zhang 1 , Xiao-Fei Zhang 1 , Lin Wang 1 , Dong-Yan Guo 1 , Jia-Min Zhang 1 , Yong-Gang Chen 1 , Zhi-Chao Wang 1 , Li-Shan Pei 1 , Jiang-Xue Chen 1 , Ya-Jun Shi 1 , Jun-Bo Zou 1
Affiliation  

Background. We provide an updated meta-analysis with detailed information on a combination of TCM and routine treatment. Methods. Retrieve appropriate articles with no language restrictions on keywords until 8 July 2019 in an electronic database. All trajectories are screened according to certain criteria. The quality of certified research was also evaluated. We made a detailed record of the results of the measurement. Meta-analysis was carried out by using the Revman 5.3 software. Results. Sixty-seven RCTs were included, and 6594 subjects were analyzed. Compared with routine treatment, the total effective rate (TER) of TCM combined with routine treatment was improved, and the recovery of stroke was also significantly accelerated. Regulation of blood lipids by notably shrinking the contents of TC, TG, and LDL and enhancing the levels of HDL. The levels of serum hs-CRP, WHV, and WLV decreased significantly, indicating that the expression of thrombomodulin was decreased after the comprehensive treatment of traditional Chinese medicines (TCMs). The combination of TCM treatment could enhance the protection of neural function by decreasing the NIHSS scoring while increasing the BI scoring. Paeoniae Radix Rubra, Angeticae Sinensis Radix, etc., can effectively improve the clinical symptoms of stroke convalescent patients and promote the recovery of neurological function. ACU of Baihui, Renzhong, etc., can improve the clinical rehabilitation effect of patients. However, our findings must be handled with care because of the small sample size and low quality of clinic trials cited. Other rigorous and large-scale RCTs are in need to confirm these results. Conclusion. A combination of TCM and routine treatment in the treatment of stroke could improve TER, and it is beneficial to the rehabilitation of patients in the recovery period of apoplexy. These effects can be mediated by a combination of several mechanisms. Nevertheless, due to the limitations of this study, these results should be handled with caution.

中文翻译:

中风恢复期中医药临床疗效分析:系统回顾与荟萃分析

背景。我们提供最新的荟萃分析,其中包含有关中医和常规治疗相结合的详细信息。方法。在 2019 年 7 月 8 日之前在电子数据库中检索没有关键字语言限制的适当文章。所有轨迹均根据一定标准进行筛选。还评估了经过认证的研究的质量。我们对测量结果做了详细记录。采用Revman 5.3软件进行Meta分析。结果。纳入了 67 项随机对照试验,分析了 6594 名受试者。与常规治疗相比,中医药联合常规治疗的总有效率(TER)提高,脑卒中康复也明显加快。调节血脂,显着降低TC、TG、LDL含量,提高HDL水平。血清hs-CRP、WHV、WLV水平均显着下降,提示中药综合治疗后血栓调节蛋白表达量下降。中药联合治疗可通过降低NIHSS评分、提高BI评分来增强对神经功能的保护。赤芍、当归等,能有效改善中风恢复期患者的临床症状,促进神经功能的恢复。百会、仁中等ACU,可以提高患者的临床康复效果。然而,由于样本量小且引用的临床试验质量低,我们的研究结果必须谨慎处理。需要其他严格的大规模随机对照试验来证实这些结果。结论。中医药与常规治疗相结合治疗中风可以提高TER,有利于中风恢复期患者的康复。这些效应可以通过多种机制的组合来介导。然而,由于本研究的局限性,这些结果应谨慎处理。
更新日期:2020-09-22
down
wechat
bug