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Analysis, identification and visualization of subgroups in genomics.
Briefings in Bioinformatics ( IF 6.8 ) Pub Date : 2020-09-21 , DOI: 10.1093/bib/bbaa217
Gunnar Völkel 1 , Simon Laban 2 , Axel Fürstberger 3 , Silke D Kühlwein 4 , Nensi Ikonomi 4 , Thomas K Hoffman 2 , Cornelia Brunner 2 , Donna S Neuberg 5 , Verena Gaidzik 6 , Hartmut Döhner 6 , Johann M Kraus 7 , Hans A Kestler 8
Affiliation  

Cancer is a complex and heterogeneous disease involving multiple somatic mutations that accumulate during its progression. In the past years, the wide availability of genomic data from patients’ samples opened new perspectives in the analysis of gene mutations and alterations. Hence, visualizing and further identifying genes mutated in massive sets of patients are nowadays a critical task that sheds light on more personalized intervention approaches.

中文翻译:

基因组学中亚组的分析、识别和可视化。

癌症是一种复杂的异质性疾病,涉及在其进展过程中积累的多个体细胞突变。在过去的几年里,患者样本中基因组数据的广泛可用性为基因突变和改变的分析开辟了新的视角。因此,可视化和进一步识别大量患者中突变的基因是当今的一项关键任务,它揭示了更个性化的干预方法。
更新日期:2020-09-22
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