There is great interest in producing nanoparticles for various applications. The objective of this work was to develop a procedure for reproducibly creating stable lead (Pb) phosphate nanoparticle aqueous suspensions. A stable 5 mg/L Pb-phosphate nanoparticle “stock” suspension was synthesized via chemical precipitation of Pb and orthophosphate in water at pH 7.5 with 4.4 mg soluble PO₄/L and 7 mg C/L dissolved inorganic carbon. The stock suspension was subsequently diluted to produce stable 0.10 mg/L Pb “challenge” water suspensions without compromising the nanoparticle size, structure, mineralogy and solubility. Specifically, the hexagonal hydroxypyromorphite nanoparticles had an average diameter of 38 nm based on transmission electron microscopy analysis and an associated Pb solubility of 0.001 mg/L. The properties of the stock suspensions were not impacted by further dilutions, and the challenge water suspensions remained stable for 24 hours. In the context of drinking water, a protocol to produce such a stable Pb nanoparticle challenge water suspension would be very useful in evaluating Pb bioavailability, identifying Pb remediation strategies, and testing filter effectiveness to remove Pb from water.

产生用于各种应用的纳米颗粒引起了极大的兴趣。这项工作的目的是开发一种可重复产生稳定的磷酸铅（Pb）纳米颗粒水悬浮液的程序。通过在pH值为7.5的水中用4.4 mg可溶性PO ₄化学沉淀Pb和正磷酸盐来合成稳定的5 mg / L Pb-磷酸盐纳米颗粒“储备”悬浮液/ L和7 mg C / L的溶解无机碳。随后将储备悬浮液稀释以产生稳定的0.10 mg / L Pb“挑战”水悬浮液，而不会影响纳米颗粒的尺寸，结构，矿物学和溶解度。具体而言，基于透射电子显微镜分析，六角形羟基焦晶石纳米粒子的平均直径为38nm，并且相关的Pb溶解度为0.001mg / L。母液悬浮液的性能不受进一步稀释的影响，挑战水悬浮液在24小时内保持稳定。在饮用水的背景下，生产这样稳定的Pb纳米颗粒挑战水悬浮液的方案对于评估Pb的生物利用度，确定Pb的修复策略以及测试从水中去除Pb的过滤器有效性非常有用。