Cardiovascular disease (CVD) is exceedingly prevalent, and occurs prematurely in individuals with bipolar disorder (BD). Cardiorespiratory fitness (CRF), arguably the most important modifiable CVD risk factor, is also associated with brain structure and function. There is a gap in knowledge regarding CRF in BD, particularly in relation to brain structure.

中文翻译：

---

双相障碍青少年心肺健康的临床和神经影像学相关性

心血管疾病 (CVD) 非常普遍，并且在患有双相情感障碍 (BD) 的个体中过早发生。心肺适能 (CRF) 可以说是最重要的可改变的 CVD 风险因素，也与大脑结构和功能有关。关于 BD 中 CRF 的知识存在差距，特别是与大脑结构相关的知识。