An outbreak of relapsing fever unmasked by microbial paleoserology, 16th century, France.,American Journal of Physical Anthropology

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An outbreak of relapsing fever unmasked by microbial paleoserology, 16th century, France.
American Journal of Physical Anthropology ( IF 2.6 ) Pub Date : 2020-09-21 , DOI: 10.1002/ajpa.24138
Hamadou Oumarou Hama _{1,

2} , Rémi Barbieri _{1,

2,

3} , Jacqueline Guirou _{1,

2} , Thomas Chenal ₄ , Aurélie Mayer ₅ , Yann Ardagna ₃ , Michel Signoli ₃ , Gérard Aboudharam _{2,

6} , Didier Raoult _{1,

2} , Michel Drancourt _{1,

2}

Affiliation

Depicting past epidemics currently relies on DNA‐based detection of pathogens, an approach limited to pathogens with well‐preserved DNA sequences. We used paleoserology as a complementary approach detecting specific antibodies under a mini line‐blot format including positive and negative control antigens.

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