Abstract In the present study, we have follwed the hydrothermal path for the synthesis of gold nanoparticles (Au NPs) from the biomaterial Elaeocarpus ganitrus seeds extract, which is a rapid, eco-friendly, non-chemical way. The prepared NPs were thoroughly analysed by powder x-ray diffraction and high resolution transmission electron microscopy studies and were also tested for anticancer studies. Besides, the antioxidant, antibacterial and anticancer properties of Au NPs were studied. In vitro studies revealed the dose-dependent cytotoxic effect of Au NPs. The prepared nanoparticles showed good cytotoxic impact against a prostate cancer (PC-3) cells line. The evidences of the current study lead to the synthesis of novel and cost-effective drugs from Elaeocarpus ganitrus seeds extract by using the bio approach.

中文翻译：

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使用新型胡麻种子提取物合成的金纳米颗粒的体外抗菌、抗氧化和细胞毒性潜力

摘要 在本研究中，我们遵循水热路径从生物材料 Elaeocarpus ganitrus 种子提取物中合成金纳米粒子 (Au NPs)，这是一种快速、环保、非化学的方法。通过粉末 X 射线衍射和高分辨率透射电子显微镜研究对制备的 NP 进行了彻底分析，并且还进行了抗癌研究测试。此外，研究了Au NPs的抗氧化、抗菌和抗癌特性。体外研究揭示了 Au NPs 的剂量依赖性细胞毒作用。制备的纳米颗粒对前列腺癌 (PC-3) 细胞系显示出良好的细胞毒性影响。当前研究的证据导致使用生物方法从 Elaeocarpus ganitrus 种子提取物合成新型且具有成本效益的药物。