Heavy metal pollution arising from agricultural and industrial activities poses a significant threat to the aquatic environment, especially the increasing levels of chromium (Cr) that is exacerbating marine pollution. Given the economic importance of the Pacific white shrimp Litopenaeus vannamei (L. vannamei), understanding the impact of marine Cr pollution is deemed to be significant. In this study, we used the transcriptome sequencing (RNA-seq) technique to characterize the molecular mechanism of Cr exposure in L. vannamei. Gene ontology enrichment analysis showed substrate-specific and ion transport-related functions were mainly influenced by Cr exposure. We further identified genes involved in protein digestion and absorption (PEPT1, BAT1, MDU1), chemical carcinogenesis (GST and UGTs), ABC transporters (ABCC2), apoptosis (CAPN1, CASP10, PARP), implying the potentially Cr disintoxication mechanisms in L. vannamei. Genes within pancreatic secretion (ALT, LDH), lysosome (CTSL and HEXB), and peroxisome (ACOX1, ECI2, NUDT12) pathways implied the potentially Cr toxicity mechanisms in L. vannamei.

由农业和工业活动引起的重金属污染对水生环境构成了重大威胁，尤其是铬（Cr）含量的增加正在加剧海洋污染。鉴于太平洋白虾南美白对虾（L. vannamei）的经济重要性，理解海洋铬污染的影响被认为是重要的。在这项研究中，我们使用了转录组测序（RNA-seq）技术来表征南美白对虾中铬暴露的分子机制。。基因本体富集分析表明，底物特异性和离子转运相关的功能主要受Cr暴露的影响。我们进一步鉴定了参与蛋白质消化和吸收的基因（PEPT1，BAT1，MDU1），化学致癌作用（GST和UGTs），ABC转运蛋白（ABCC2），细胞凋亡（CAPN1，CASP10，PARP），这暗示了L中潜在的Cr解毒机理。南美白对虾。胰腺分泌（ALT，LDH），溶酶体（CTSL和HEXB）和过氧化物酶体（ACOX1，ECI2，NUDT12）途径内的基因暗示了南美白对虾的潜在Cr毒性机制。