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Time-dependent solution of the NIMFA equations around the epidemic threshold.
Journal of Mathematical Biology ( IF 1.9 ) Pub Date : 2020-09-22 , DOI: 10.1007/s00285-020-01542-6
Bastian Prasse 1 , Piet Van Mieghem 1
Affiliation  

The majority of epidemic models are described by non-linear differential equations which do not have a closed-form solution. Due to the absence of a closed-form solution, the understanding of the precise dynamics of a virus is rather limited. We solve the differential equations of the N-intertwined mean-field approximation of the susceptible-infected-susceptible epidemic process with heterogeneous spreading parameters around the epidemic threshold for an arbitrary contact network, provided that the initial viral state vector is small or parallel to the steady-state vector. Numerical simulations demonstrate that the solution around the epidemic threshold is accurate, also above the epidemic threshold and for general initial viral states that are below the steady-state.



中文翻译:

NIMFA方程在流行阈值附近的时间相关解。

多数流行病模型由不具有封闭形式解的非线性微分方程描述。由于不存在封闭形式的解决方案,因此对病毒精确动态的理解相当有限。我们以任意接触网络的流行阈值为中心,以围绕流行阈值的异构扩散参数,对易感性感染易感流行过程的N交织平均场近似的微分方程进行求解,前提是初始病毒状态向量较小或与稳态向量。数值模拟表明,在流行阈值附近的解决方案是准确的,也高于流行阈值,并且对于低于稳态的一般初始病毒状态也是如此。

更新日期:2020-09-22
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