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Assessment of tobacco heating system 2.4 on osteogenic differentiation of mesenchymal stem cells and primary human osteoblasts compared to conventional cigarettes.
World Journal of Stem Cells ( IF 3.6 ) Pub Date : 2020-9-22 , DOI: 10.4252/wjsc.v12.i8.841
Romina H Aspera-Werz 1 , Sabrina Ehnert 2 , Monja Müller 2 , Sheng Zhu 2 , Tao Chen 2 , Weidong Weng 2 , Johann Jacoby 3 , Andreas K Nussler 2
Affiliation  

Cigarette smoking (CS) is the most common method of consuming tobacco. Deleterious effects on bone integrity, increased incidence of fractures, and delayed fracture healing are all associated with CS. Over 150 of the 6500 molecular species contained in cigarette smoke and identified as toxic compounds are inhaled by CS and, via the bloodstream, reach the skeletal system. New technologies designed to develop a reduced-risk alternative for smokers are based on electronic nicotine delivery systems, such as e-cigarettes and tobacco heating systems (THS). THS are designed to heat tobacco instead of burning it, thereby reducing the levels of harmful toxic compounds released.

中文翻译:

与常规香烟相比,评估烟草加热系统2.4对间充质干细胞和人类原代成骨细胞成骨分化的影响。

抽烟(CS)是最常见的烟草消费方法。对骨完整性的有害影响,增加的骨折发生率和延迟的骨折愈合都与CS有关。CS吸入香烟烟雾中包含的被识别为有毒化合物的6500个分子种类中的150多个,并通过血流到达骨骼系统。旨在为吸烟者开发低风险替代品的新技术基于电子尼古丁传送系统,例如电子烟和烟草加热系统(THS)。THS旨在加热烟草而不是燃烧烟草,从而降低了释放的有害有毒化合物的水平。
更新日期:2020-09-23
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