当前位置: X-MOL 学术Sleep Biol. Rhythm. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
The influential factor of narcolepsy on quality of life: compared to obstructive sleep apnea with somnolence or insomnia
Sleep and Biological Rhythms ( IF 1.0 ) Pub Date : 2019-08-26 , DOI: 10.1007/s41105-019-00237-w
Mei Ling Song , Keun Tae Kim , Gholam K. Motamedi , Yong Won Cho

Narcoleptics tend to have a low quality of life (QoL). Few studies have compared QoL in narcolepsy against other sleep disorders. The purpose of this study was to investigate QoL and its influential factors in narcolepsy patients compared to obstructive sleep apnea (OSA) with somnolence and primary insomnia. We enrolled 63 narcoleptics (33 type 1, 30 type 2), 49 patients with OSA with somnolence, and 87 insomniacs. All patients were diagnosed through detailed clinical face-to-face interviews and polysomnography and had no other comorbid sleep disorders or medical diseases. All patients completed the Korean-version of the Short-Form 36-Item Health Survey (K-SF36) and a series of standard sleep-related questionnaires. The QoL of the narcolepsy group was comparable to the OSA with somnolence and insomnia groups. There was no significant difference between type 1 and type 2 narcolepsy on the total score of the K-SF36. However, factors that had the most impact on QoL included anxiety followed by depressive mood for narcoleptics, depressive mood followed by severity of insomnia for OSA with somnolence, and insomnia severity followed by depressive mood for insomniacs. Mood disturbances, mainly anxiety, affected QoL most in narcolepsy patients. Excessive daytime sleepiness and nocturnal sleep disturbance did not directly affect QoL of narcoleptics. To improve QoL in narcoleptics, proper management of anxiety should be considered as part of the treatment.

中文翻译:

发作性睡病对生活质量的影响因素:与阻塞性睡眠呼吸暂停伴嗜睡或失眠相比

发作性睡病患者的生活质量 (QoL) 往往较低。很少有研究将发作性睡病的 QoL 与其他睡眠障碍进行比较。本研究的目的是调查嗜睡和原发性失眠与阻塞性睡眠呼吸暂停 (OSA) 相比,发作性睡病患者的 QoL 及其影响因素。我们招募了 63 名发作性睡病患者(33 名 1 型、30 名 2 型)、49 名患有嗜睡的 OSA 患者和 87 名失眠症患者。所有患者均通过详细的临床面对面访谈和多导睡眠图诊断,没有其他共病睡眠障碍或内科疾病。所有患者都完成了韩文版 36 项健康调查 (K-SF36) 和一系列标准的睡眠相关问卷。发作性睡病组的 QoL 与具有嗜睡和失眠组的 OSA 相当。在 K-SF36 的总分上,1 型和 2 型发作性睡病之间没有显着差异。然而,对 QoL 影响最大的因素包括:对于发作性睡病患者,焦虑其次是抑郁情绪,对于伴有嗜睡的 OSA,抑郁情绪其次是失眠的严重程度,以及对于失眠症患者,失眠的严重程度其次是抑郁情绪。情绪障碍,主要是焦虑,对发作性睡病患者的 QoL 影响最大。白天过度嗜睡和夜间睡眠障碍不会直接影响发作性睡病患者的生活质量。为了改善发作性睡病患者的生活质量,应将适当的焦虑管理作为治疗的一部分。对于伴有嗜睡的 OSA,抑郁情绪随后是失眠的严重程度,对于失眠症患者,失眠严重程度随后是抑郁情绪。情绪障碍,主要是焦虑,对发作性睡病患者的 QoL 影响最大。白天过度嗜睡和夜间睡眠障碍不会直接影响发作性睡病患者的生活质量。为了改善发作性睡病患者的生活质量,应将适当的焦虑管理作为治疗的一部分。对于伴有嗜睡的 OSA,抑郁情绪随后是失眠的严重程度,对于失眠症患者,失眠严重程度随后是抑郁情绪。情绪障碍,主要是焦虑,对发作性睡病患者的 QoL 影响最大。白天过度嗜睡和夜间睡眠障碍不会直接影响发作性睡病患者的生活质量。为了改善发作性睡病患者的生活质量,应将适当的焦虑管理作为治疗的一部分。
更新日期:2019-08-26
down
wechat
bug