Abstract

In order to improve the patient’s condition, the transfusion of blood products is used, however, there are problems with blood transfusion including infections, immune suppression, allergic reactions and anaphylactic shock-related to leukemia and plasma product. Cytokine can now be an appropriate choice to reduce the need for blood transfusion. Various types of cytokines have been studied in human clinical trials and some of them have a substantial function to decrease blood transfusion. In this study, we have investigated the important cytokines involved in reducing cells (Red blood cells and platelets) transfusion. First, we have investigated the cytokines involved in erythropoiesis and thrombopoiesis and covered some clinical studies about them. The second side effects of the administration of these cytokines have been addressed, and finally, we have suggested some recommendations about cytokine therapy.

中文翻译：

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输血中运行细胞因子和输血的细胞因子疗法的雕像

摘要

为了改善患者的状况，使用了输血产品，但是输血存在一些问题，包括感染，免疫抑制，变态反应以及与白血病和血浆产品有关的过敏性休克。现在，细胞因子可以作为减少输血需求的合适选择。在人类临床试验中已经研究了各种类型的细胞因子，其中一些具有减少输血的重要功能。在这项研究中，我们研究了参与减少细胞（红细胞和血小板）输血的重要细胞因子。首先，我们研究了涉及红细胞生成和血小板生成的细胞因子，并涵盖了一些有关它们的临床研究。这些细胞因子给药的第二个副作用已经解决，最后，