Background. Foodborne diseases (FBD) caused by resistant pathogens are a global public health problem. One main driver of the increasing FBD incidence is the transfer of pathogenic organisms from animal guts to carcasses during processing and subsequent transfer from meat products to consumers. Methods. In this study, meat samples from abattoirs in the formal meat sector (FMS) () and slaughter points in the informal meat sector (IMS) () were collected for microbial detection and phenotypic AMR determination using polymerase chain reaction. Results. The antibiogram of Staphylococcus aureus isolates revealed that resistance to clindamycin (74.3%) and ampicillin (59.5%) was highest in the FMS, while resistance to penicillin (83.8%) and tetracycline (82.1%) was highest in the IMS. Escherichia coli isolates show significant resistance to chloramphenicol (90.7%) and tetracycline (82.3%) in the FMS. Likewise, resistance to tetracycline (92.3%) and sulfamethoxazole/trimethoprim (87.5%) was highest in the IMS. The multiple antibiotic resistance index (MARI) for S. aureus and E. coli ranged from 0.3 to 0.8 and 0.2 to 0.5, respectively. Conclusion. This study suggests high-level contamination of meat with resistant pathogens and highlights the public health consequences associated with consuming such unhygienic products.

中文翻译：

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从南非正规和非正规部门的肉类中获得的金黄色葡萄球菌和大肠杆菌分离株的抗菌素耐药性表型


背景。由耐药病原体引起的食源性疾病（FBD）是一个全球性的公共卫生问题。 FBD发病率增加的一个主要驱动因素是病原微生物在加工过程中从动物肠道转移到屠体，并随后从肉制品转移到消费者手中。方法。在这项研究中，来自正规肉类部门 (FMS) 屠宰场的肉类样本（ ）和非正规肉类部门（IMS）的屠宰点（ ）收集用于微生物检测和使用聚合酶链反应测定表型 AMR。结果。金黄色葡萄球菌分离株的抗菌谱显示，FMS 中对克林霉素 (74.3%) 和氨苄西林 (59.5%) 的耐药性最高，而 IMS 中对青霉素 (83.8%) 和四环素 (82.1%) 的耐药性最高。 FMS 中分离出的大肠杆菌对氯霉素 (90.7%) 和四环素 (82.3%) 表现出显着的耐药性。同样，IMS 中对四环素 (92.3%) 和磺胺甲恶唑/甲氧苄啶 (87.5%) 的耐药性最高。 S的多重抗生素耐药性指数 (MARI)。金黄色葡萄球菌和大肠杆菌。大肠杆菌的范围分别为0.3至0.8和0.2至0.5。结论。这项研究表明肉类受到耐药病原体的高度污染，并强调了与消费此类不卫生产品相关的公共卫生后果。