An organ donor PaO2 above 40 kPa is generally required for lung transplantation. Point-of-care (POC) blood gas analyzers are commonly used by organ procurement organizations (OPO) but may underestimate the PaO2 at high levels. We hypothesized that changing to a more accurate blood gas analyzer would result in additional lungs transplanted. All PaO2 measurements on organ donors managed at one OPO’s recovery center were performed on an i-STAT POC analyzer prior to October 2015, and on a GEM 4000 subsequently. For 24 weeks, all blood gases were tested simultaneously on both analyzers. We compared lung outcomes of 147 donors in the year prior to this change (using the i-STAT) with 56 donors in the 24-week study period (using the GEM 4000 for lung allocation). When the PaO2 was above 40 kPa, the i-STAT PaO2 was 7.2 kPa lower on average than the GEM 4000. When the GEM PaO2 measured between 40 and 50 kPa, the corresponding i-STAT PaO2 value registered less than 40 kPa 25 out of 48 times (52%), with an average difference of 7.3 kPa (SD = 2.9). The rate of lungs transplanted using the GEM 4000 was 48% compared with 35% in the year prior using the i-STAT (p = .11), with equivalent recipient outcomes. The i-STAT analyzer underestimated the PaO2 above 40 kPa and changing to a more accurate PaO2 analyzer may increase lungs transplanted.

肺移植通常需要高于40 kPa的器官供体PaO2。器官采购组织（OPO）通常使用即时医疗（POC）血气分析仪，但可能会低估PaO2的含量。我们假设更换为更准确的血气分析仪会导致额外的肺移植。在2015年10月之前，使用i-STAT POC分析仪对在一个OPO回收中心管理的器官供体进行的所有PaO2测量，随后在GEM 4000上进行。在24周内，在两个分析仪上同时测试了所有血气。我们比较了这一变化之前一年中147位捐献者的肺结局（使用i-STAT）与24周研究期内56位捐献者的肺结局（使用GEM 4000进行肺分配）。当PaO2高于40 kPa时，i-STAT PaO2为7。平均比GEM 4000低2 kPa。当GEM PaO2在40至50 kPa之间时，对应的i-STAT PaO2值记录不到40 kPa，其中48次（52％）小于25 kPa，平均差为7.3 kPa （SD = 2.9）。使用GEM 4000的肺移植率为48％，而使用i-STAT的前一年为35％（p  = .11），接受者的结果相同。i-STAT分析仪低估了40 kPa以上的PaO2，更换为更准确的PaO2分析仪可能会增加肺移植。