We use the dynamic electroencephalography–functional magnetic resonance imaging (EEG‐fMRI) method to incorporate variability in the amplitude and field of the interictal epileptic discharges (IEDs) into the fMRI analysis. We ask whether IED variability analysis can (a) identify additional activated brain regions during the course of IEDs, not seen in standard analysis; and (b) demonstrate the origin and spread of epileptic activity. We explore whether these functional changes recapitulate the structural connections and propagation of epileptic activity during seizures.

中文翻译：

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癫痫发作期间 fMRI 激活的动态分析可以帮助确定癫痫发作的起源

我们使用动态脑电图 - 功能磁共振成像 (EEG-fMRI) 方法将发作间期癫痫放电 (IED) 的幅度和场的可变性纳入 fMRI 分析。我们询问 IED 变异性分析是否可以 (a) 在 IED 过程中识别其他激活的大脑区域，这在标准分析中是看不到的；(b) 证明癫痫活动的起源和传播。我们探索这些功能变化是否概括了癫痫发作期间癫痫活动的结构连接和传播。