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Corrigendum: An Excimer Clamp for Measuring Damaged‐Base Excision by the DNA Repair Enzyme NTH1
Angewandte Chemie International Edition ( IF 16.6 ) Pub Date : 2020-09-21 , DOI: 10.1002/anie.202008220 Yong Woong Jun , David L. Wilson , Anna M. Kietrys , Elizabeth R. Lotsof , Savannah G. Conlon , Sheila S. David , Eric T. Kool
中文翻译：
更正：用DNA修复酶NTH1测量碱基切除的准分子钳
Angewandte Chemie International Edition ( IF 16.6 ) Pub Date : 2020-09-21 , DOI: 10.1002/anie.202008220 Yong Woong Jun , David L. Wilson , Anna M. Kietrys , Elizabeth R. Lotsof , Savannah G. Conlon , Sheila S. David , Eric T. Kool
In Figure 1 and the graphical abstract of this Communication, the oligonucleotide probe structure was misdrawn. Below are the revised Figure 1 and the corrected graphical abstract.
Figure 1
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a) Scheme showing pyrimidine damage in DNA by oxidation and its repair by NTH1. b) The design of a GPE DNA probe and c) illustration of the sensing part showing a “clamp” of pyrenes around the damaged base, yielding a change in fluorescence emission after enzymatic excision of the damage.
中文翻译：
更正：用DNA修复酶NTH1测量碱基切除的准分子钳
在图1和此交流的图形摘要中，寡核苷酸探针的结构被错误绘制。以下是修改后的图1和更正的图形摘要。
图1
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a）示意图显示嘧啶嘧啶被DNA氧化并被NTH1修复。b）GPE DNA探针的设计和c）感应部分的示意图，显示了受损碱基周围of的“钳位”，在酶促切除后，荧光发射发生了变化。
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