A surface ion-imprinting polymer (IIP) based on Fe₃O₄/SiO₂/CS was selected to modify the glassy carbon electrode (Fe₃O₄/SiO₂/CS/Nafion/GCE), and the sensor exhibits ultrasensitive and highly selective to monitor trace level of Cu (II). SiO₂ was homogeneously coated on the Fe₃O₄ magnetic core to enhance the resistance in the harsh environment, especially various acids in the real environment. After that, chitosan film, incorporating copper ions as template ions, covered the Fe₃O₄/SiO₂ and cross-linked with glutaraldehyde. The prepared electrode was used as a working electrode to construct an electrochemical sensor for detecting trace Cu (II) and amplifying the electrochemical signal through the formation of the ion imprinted polymer. The Fe₃O₄/SiO₂/CS/Nafion/GCE IIP based sensors were characterized by XRD, FT-IR, SEM, and TGA. During the electrochemical measurement, different experimental parameters were optimized, and the sensors exhibited a wide linear detection range (0.01 to 20 μmol L⁻¹) and low limit of detection (5 nmol L⁻¹). Besides that, the sensors also demonstrated highly selective to Cu ion, comparing with other interfering ions. The Fe₃O₄/SiO₂/CS/Nafion/GCE-IIP based sensor displayed notable reproducibility and the RSD was 3.3%. The sensors based on Fe₃O₄/SiO₂/CS ion imprinted polymer have the potential to monitor other toxic metal ion pollution in harsh environment.

选择基于Fe ₃ O ₄ / SiO ₂ / CS的表面离子印迹聚合物（IIP）来修饰玻璃碳电极（Fe ₃ O ₄ / SiO ₂ / CS / Nafion / GCE），并且传感器表现出超灵敏和具有高度选择性，可监测痕量的Cu（II）。SiO ₂被均匀地涂覆在Fe ₃ O ₄磁芯上，以增强在恶劣环境中的电阻，特别是在实际环境中的各种酸。之后，以铜离子为模板离子的壳聚糖膜覆盖了Fe ₃ O ₄ / SiO _2。并与戊二醛交联。所制备的电极用作工作电极，以构建用于检测痕量铜（II）并通过形成离子印迹聚合物来放大电化学信号的电化学传感器。基于Fe ₃ O ₄ / SiO ₂ / CS / Nafion / GCE IIP的传感器通过XRD，FT-IR，SEM和TGA进行了表征。在电化学测量过程中，优化了不同的实验参数，传感器的线性检测范围宽（0.01至20μmolL ^-1），检测下限低（5 nmol L ^-1）。除此之外，与其他干扰离子相比，传感器对铜离子的选择性也很高。铁₃ O_基于4 / SiO ₂ / CS / Nafion / GCE-IIP的传感器显示出显着的可重复性，RSD为3.3％。基于Fe ₃ O ₄ / SiO ₂ / CS离子印迹聚合物的传感器具有监测恶劣环境中其他有毒金属离子污染的潜力。