Myrciaria glazioviana, which belongs to the Myrtaceae family, is used in folk medicine as an anti-inflammatory and analgesic. Previous studies have shown that this species has antibacterial, antifungal and antinociceptive activities. The objectives of this study were to evaluate the anti-inflammatory activity of the ethanolic extract of the fruit of M. glazioviana using in vivo models, to quantify the total phenol and flavonoid contents and to identify compounds in the extract. The anti-inflammatory activity was evaluated using the mice model of paw edema that was induced by different phlogistic agents: carrageenan, prostaglandin E2, bradykinin and a synthetic compound named compound 48/80. The extract was subjected to colorimetric tests to quantify phenols and flavonoids and the compounds in the extract were identified using direct insertion mass spectrometry (ESI-MS/MS). The presence of phenols and flavonoids were found, specifically 5 compounds: quercetin, dihydroquercetin, gallic acid, quinic acid, and ascorbic acid. The extract of M. glazioviana of 250 and 125 mg/kg showed antidematogenic activity in the carrageenan, prostaglandin E2 and compound 48/80 models of paw edema, since the groups treated with the extract showed minor edema in relation to the saline groups. These results may be directly related to the compounds identified in the extract, as indicated by previous studies using such compounds. These results showed the pharmacological potential of this species, which in addition to corroborating its use in folk medicine, suggested the potential of these fruits to be used as a nutraceutical.

属于Myrtaceae家族的Myrciaria glazioviana在民间医学中用作抗炎和止痛药。先前的研究表明，该物种具有抗菌，抗真菌和镇痛作用。这项研究的目的是评估体内使用M. glazioviana果实的乙醇提取物的抗炎活性。模型，以量化总酚和类黄酮含量并鉴定提取物中的化合物。使用由不同的发炎剂：角叉菜胶，前列腺素E2，缓激肽和名为化合物48/80的合成化合物诱导的爪水肿的小鼠模型评估抗炎活性。对提取物进行比色测试以定量酚和类黄酮，并使用直接插入质谱（ESI-MS / MS）鉴定提取物中的化合物。发现存在酚和类黄酮，特别是5种化合物：槲皮素，二氢槲皮素，没食子酸，奎尼酸和抗坏血酸。M. glazioviana的提取物在角叉菜胶，前列腺素E2和化合物48/80的爪水肿模型中，250 mg / kg和125 mg / kg的苯丙胺显示出抗脱皮活性，因为与盐水组相比，用提取物处理的组显示出较小的水肿。这些结果可能与提取物中鉴定出的化合物直接相关，如先前使用此类化合物的研究所表明的那样。这些结果表明该物种的药理潜力，除了证实其在民间医学中的用途外，还暗示了这些水果可用作营养保健品的潜力。