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Sand bath assisted green synthesis of carbon dots from citrus fruit peels for free radical scavenging and cell imaging
Colloids and Surfaces B: Biointerfaces ( IF 5.4 ) Pub Date : 2020-09-21 , DOI: 10.1016/j.colsurfb.2020.111362
Krishna Kanthi Gudimella , Tejaswini Appidi , Hui-Fen Wu , B Venkateswararao , Anil Jogdand , Aravind Kumar Rengan , Gangaraju Gedda

A sand bath assisted strategy for the synthesis of fluorescent carbon dots (CDs) using citrus fruit peels as a renewable green resource is reported in this work. The CDs were synthesized without any alkaline or acidic environment. The synthesized CDs were characterized by various spectroscopic and microscopy techniques. The CDs exhibited excellent water solubility and superior optical properties like excitation dependent emission, and multicolor fluorescence. In addition, the CDs have exhibited remarkable free radical scavenging activity (EC50: 4.7382 μg ml−1).The CDs were highly biocompatible and showed lower toxicity. The CDs when modified with folic acid have shown a significant potential as biological labels for cellular imaging at multiple excitations. Synthesis of CDs from natural fruit peels as an excellent carbon source for versatile applications has been demonstrated.



中文翻译:

沙浴辅助从柑桔果皮中绿色合成碳点,用于自由基清除和细胞成像

在这项工作中,报道了使用柑橘果皮作为可再生绿色资源的沙浴辅助策略,用于合成荧光碳点(CD)。合成CD时没有任何碱性或酸性环境。合成的CD通过各种光谱学和显微镜技术进行了表征。CD表现出出色的水溶性和出色的光学特性,如激发依赖性发射和多色荧光。此外,CD还显示出显着的自由基清除活性(EC 50:4.7382μgml -1CD具有高度生物相容性且毒性较低。当用叶酸修饰的CD表现出了巨大的潜力,可以作为多种激发下细胞成像的生物标记。已经证明了从天然果皮合成CD可以作为多种用途的极佳碳源。

更新日期:2020-10-08
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