Genome editing is revolutionising the field of genetics, which includes novel applications to food animals. Responsible research and innovation (RRI) has been advocated as a way of ensuring that a wider-range of stakeholders and publics are able to engage with new and emerging technologies to inform decision making from their perspectives and values. We posit that genome editing is now proceeding at such a fast rate, and in so many different directions, such as to overwhelm attempts to achieving a more reflective pace. An alternative location for reflection is during the much slower process of taking products from the lab to market. We suggest emphasising Responsible Innovation, putting the ‘I’ back into RRI, and encouraging companies to embrace an RRI approach. We review some previous attempts at developing industry-relevant frameworks for RRI. We then describe two examples of genome editing in livestock; hornless cattle and disease resistant pigs, and reflect on the sorts of questions that could be considered in these two genome editing examples. This paper seeks to take forward the discussion on RRI by extending it to bringing products to market in the context of genome edited livestock.

中文翻译：

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基因组编辑和负责任的创新，它们可以调和吗？

基因组编辑正在彻底改变遗传学领域，其中包括对食用动物的新应用。负责任的研究和创新 (RRI) 被提倡作为一种方式，以确保更广泛的利益相关者和公众能够参与新兴技术，从他们的观点和价值观为决策提供信息。我们假设基因组编辑现在正以如此快的速度在如此多的不同方向上进行，例如压倒实现更具反思性步伐的尝试。另一个反思的地点是将产品从实验室推向市场的过程要慢得多。我们建议强调负责任的创新，将“我”放回 RRI，并鼓励公司采用 RRI 方法。我们回顾了之前为 RRI 开发与行业相关的框架的一些尝试。然后我们描述了牲畜基因组编辑的两个例子；无角牛和抗病猪，并思考在这两个基因组编辑示例中可以考虑的各种问题。本文旨在推进对 RRI 的讨论，将其扩展到在基因组编辑牲畜的背景下将产品推向市场。