In this work, a solely gravity and capillary force-driven flow chemiluminescence (GCF-CL) paper-based microfluidic device has been proved for the first time as a new platform for inexpensive, usable, minimally-instrumented dynamic chemiluminescence (CL) detection of chromium (III) [Cr(III)], where an appropriate angle of inclination between the loading and detection zones on the paper produces a rapid flow of CL prompt solution through the paper channel. For this study, we use a cost-effective paper device that is manufactured by a simple wax screen-printing method, while the signal generated from the Cr(III)-catalyzed oxidation of luminol by H2O2is recorded by a low-cost and luggable CCD camera. A series of GCF-CL affecting factors have been evaluated carefully. At optimal conditions, two linear relationships between GCF-CL intensities and the logarithms of Cr(III) concentrations are obtained in the concentration ranges of 0.025–35[Formula: see text]mg/L and 50–500[Formula: see text]mg/L separately, with the detection limit of 0.0245[Formula: see text]mg/L for a less than 30[Formula: see text]s assay, and relative standard deviations (RSDs) of 3.8%, 4.5% and 2.3% for 0.75, 5 and 50[Formula: see text]mg/L of Cr(III) ([Formula: see text]). The above results indicate that the GCF-CL paper-based microfluidic device possesses a receivable sensitivity, dynamic range, storage stability and reproducibility. Finally, the developed GCF-CL is utilized for Cr(III) detection in real water samples.

中文翻译：

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一种用于检测水中铬（III）的流动化学发光纸基微流控装置

在这项工作中，首次证明了一种完全重力和毛细力驱动的流动化学发光 (GCF-CL) 纸基微流体装置作为廉价、可用、最少仪器的动态化学发光 (CL) 检测的新平台。铬 (III) [Cr(III)]，其中纸上的加载区和检测区之间的适当倾斜角会产生 CL 快速溶液通过纸通道的快速流动。在这项研究中，我们使用了一种通过简单的蜡丝网印刷方法制造的具有成本效益的纸装置，而 H2○2由低成本和便携的 CCD 相机记录。对一系列 GCF-CL 影响因素进行了仔细评估。在最佳条件下，在0.025-35[公式：见正文]mg/L和50-500[公式：见正文]的浓度范围内，得到GCF-CL强度与Cr(III)浓度对数之间的两个线性关系mg/L，检出限为 0.0245[公式：见文]mg/L，小于 30[公式：见文]s 测定，相对标准偏差 (RSD) 分别为 3.8%、4.5% 和 2.3%对于 0.75、5 和 50[公式：见正文]mg/L 的 Cr(III)（[公式：见正文]）。上述结果表明，GCF-CL纸基微流控器件具有可接受的灵敏度、动态范围、储存稳定性和重现性。最后，开发的 GCF-CL 用于真实水样中的 Cr(III) 检测。