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Chromone Derivatives from the Twigs of
Heterocycles ( IF 0.8 ) Pub Date : 2020-09-18 , DOI: 10.3987/com-20-14335
Qiu-Fen Hu , Yu-Ping Wu , Guang-Hui Kong , Zhen-Yuan Xia , Fan Wu , Ya-Ning Zhu , Jing Li , Wei-Song Kong , Min Zhou , Guang-Yu Yang

Three new (1 - 3), together with four known chromone derivatives (4 - 7) were isolated from the twigs of Cassia agnes. Their structures were elucidated by spectroscopic methods, including extensive 1D- and 2D-NMR techniques. Compounds 1 - 7 were evaluated for their anti-rotavirus activity. The results revealed that compounds 1 - 7 exhibited potent anti-rotavirus activity with TI valves in the range of 9.4 - 14.5, respectively.

中文翻译:

细枝中的色酮衍生物

决明子的小枝中分离出三个新的(1-3)和四个已知的色酮衍生物(4-7)。通过包括广泛的1D和2D-NMR技术在内的光谱方法阐明了它们的结构。评价化合物1-7的抗轮状病毒活性。结果表明,化合物1-7在TI瓣膜分别在9.4-14.5的范围内表现出强大的抗轮状病毒活性。
更新日期:2020-09-18
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