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Long-read only assembly of Drechmeria coniospora genomes reveals widespread chromosome plasticity and illustrates the limitations of current nanopore methods.
GigaScience ( IF 11.8 ) Pub Date : 2020-09-18 , DOI: 10.1093/gigascience/giaa099
Damien Courtine 1 , Jan Provaznik 2 , Jerome Reboul 1 , Guillaume Blanc 3 , Vladimir Benes 2 , Jonathan J Ewbank 1
Affiliation  

Long-read sequencing is increasingly being used to determine eukaryotic genomes. We used nanopore technology to generate chromosome-level assemblies for 3 different strains of Drechmeria coniospora, a nematophagous fungus used extensively in the study of innate immunity in Caenorhabditis elegans.

中文翻译:


Drechmeria coniospora 基因组的长只读组装揭示了广泛的染色体可塑性,并说明了当前纳米孔方法的局限性。



长读长测序越来越多地用于确定真核基因组。我们使用纳米孔技术为 3 种不同的Drechmeria coniospora菌株生成染色体级组装,Drechmeria coniospora 是一种广泛用于秀丽隐杆线虫先天免疫研究的食线虫真菌。
更新日期:2020-09-20
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