Cancer-related cognitive impairment (CRCI) is a significant comorbidity for cancer patients and survivors. Physical activity (PA) has been found to be a strong gene modulator that can induce structural and functional changes in the brain. PA and exercise reduce the risk of cancer development and progression and has been shown to help in overcoming post-treatment syndromes. Exercise plays a role in controlling cancer progression through direct effects on cancer metabolism. In this review, we highlight several priorities for improving studies on CRCI in patients and its underlying potential metabolic mechanisms.

中文翻译：

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运动可能会影响癌症相关认知障碍的新陈代谢。


癌症相关认知障碍（CRCI）是癌症患者和幸存者的重要合并症。人们发现体力活动（PA）是一种强大的基因调节剂，可以诱导大脑结构和功能的变化。 PA 和运动可降低癌症发生和进展的风险，并已被证明有助于克服治疗后综合症。运动通过直接影响癌症代谢在控制癌症进展中发挥作用。在这篇综述中，我们强调了改进患者 CRCI 及其潜在代谢机制研究的几个优先事项。