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Digital breast tomosynthesis improves diagnostic accuracy of breast microcalcifications
International Journal of Imaging Systems and Technology ( IF 3.0 ) Pub Date : 2020-09-18 , DOI: 10.1002/ima.22481
Weimin Liu 1 , Meijun Long 2 , Lingrong Peng 1 , Caihong Qu 3 , Ruomi Guo 1 , Zhuang Kang 1 , Jin Wang 1 , Juekun Wu 2 , Xiaohong Wang 1
Affiliation  

DBT reconstructs high‐resolution tomographic images through multi‐angle scanning. We aimed at investigating the diagnostic value of DBT in breast microcalcifications of Asian women. The clinical characteristics and diagnostic accuracy of FFDM and DBT in 70 breast cancer patients were compared. 52 malignant lesions and 24 benign lesions were found in 76 breast microcalcifications. FFDM presented with high sensitivity and low specificity of 94.2% and 45.8%, while DBT presented with high sensitivity and medium specificity of 96.1% and 62.5%. The positive predictive value, negative predictive value, and diagnostic coincidence rate of DBT were higher than those of FFDM (84.7%, 88.2%, 85.5% vs. 79.0%, 78.5%, 78.9%, respectively). The AUC of DBT was significantly higher than that of FFDM (Z = 2.322, P = 0.020), at 0.700 ± 0.055 [0.584‐0.800] and 0.793 ± 0.052 [0.685‐0.878], respectively. Thus, we concluded that DBT improves the diagnostic accuracy and detection rate of microcalcifications in Asian women.

中文翻译:

数字化乳房断层融合术可提高乳房微钙化的诊断准确性

DBT通过多角度扫描来重建高分辨率的断层图像。我们旨在研究DBT在亚洲女性乳房微钙化中的诊断价值。比较了FFDM和DBT在70例乳腺癌患者中的临床特征和诊断准确性。在76个乳腺微钙化中发现了52个恶性病变和24个良性病变。FFDM具有高灵敏度和低特异性,分别为94.2%和45.8%,而DBT具有高灵敏度和中特异性,分别为96.1%和62.5%。DBT的阳性预测值,阴性预测值和诊断符合率均高于FFDM(分别为84.7%,88.2%,85.5%和79.0%,78.5%,78.9%)。DBT的AUC显着高于FFDM(Z = 2.322,P = 0.020),分别为0.700±0.055 [0.584-0.800]和0。分别为793±0.052 [0.685-0.878]。因此,我们得出结论,DBT可以提高亚洲女性微钙化的诊断准确性和检出率。
更新日期:2020-09-18
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