Base editors have drawn considerable academic and industrial attention in recent years because of their ability to alter single DNA bases with precision. However, the existing cytosine and adenine base editors can only install transition mutations. Three recent studies (Kurt et al., Zhao et al., and Chen et al.) expand the base editing toolbox by developing cytosine transversion base editors.

中文翻译：

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基础编辑环境扩展到执行转换突变。

近年来，由于碱基编辑者能够精确地改变单个DNA碱基，因而引起了学术界和工业界的广泛关注。但是，现有的胞嘧啶和腺嘌呤碱基编辑器只能安装过渡突变。最近的三项研究（科特等人，赵等人，和陈等人。）扩大基地通过开发胞嘧啶碱基颠编辑编辑工具箱。