Studies suggest that the presence of endometriosis may lead to impaired ovarian reserve, while results evaluating the changes in antral follicle count (AFC) in endometriosis remain controversial. A systematic search returned 15 studies, of which nine compared AFC between patients with and without endometriosis, five articles reported differences in AFC between affected and unaffected ovaries in patients with unilateral ovarian endometriosis and one reported both of the above two situations. Overall results showed a significant decrease in AFC and anti-Müllerian hormone (AMH) and increase in serum FSH concentrations in patients with endometriosis when compared with controls. Additionally, the AFC for the ovary with the endometrioma was also significantly lower than that of the contralateral ovary in patients with unilateral ovarian endometriosis. Moreover, it appears that the AFC in patients with endometriosis where the ovaries are not affected or in early stage were not significantly different in the control group. These findings demonstrate that endometriosis is associated with reduced AFC and AMH and elevated serum concentrations of FSH, suggesting a reduction in ovarian reserve in patients with endometriosis, especially in those with ovarian endometrioma and advanced stage.

研究表明，子宫内膜异位症的存在可能导致卵巢储备功能受损，而评估子宫内膜异位症中窦卵泡计数 (AFC) 变化的结果仍存在争议。系统搜索返回 15 项研究，其中 9 项比较了子宫内膜异位症患者和非子宫内膜异位症患者的 AFC，5 篇文章报道了单侧卵巢子宫内膜异位症患者受影响和未受影响卵巢之间的 AFC 差异，1 篇报道了上述两种情况。总体结果显示，与对照组相比，子宫内膜异位症患者的 AFC 和抗苗勒管激素 (AMH) 显着降低，血清 FSH 浓度增加。此外，患有子宫内膜异位症的卵巢的 AFC 也显着低于单侧卵巢子宫内膜异位症患者的对侧卵巢。此外，卵巢未受影响或处于早期的子宫内膜异位症患者的AFC似乎与对照组没有显着差异。这些发现表明，子宫内膜异位症与 AFC 和 AMH 降低以及 FSH 血清浓度升高有关，表明子宫内膜异位症患者的卵巢储备减少，尤其是卵巢子宫内膜异位症和晚期患者。