Uncertainty in real-world situations disrupts operations, including the collection process in closed-loop supply chains (CLSCs). A collection disruption is more critical in the pharmaceutical sector since pharmaceutical leftovers contain chemicals that threaten the environment and human health. This paper revolves around the challenges of a real pharmaceutical case that implements circular economy principles through a closed-loop system design, takes sustainability issues into account, and seeks for effective management of collection disruption. The case includes a manufacturer, who invests in green research and development (R&D), and two retailers competing on corporate social responsibility (CSR) efforts to boost the collection amount and market demand. This competitive environment raises conflict of interests and complicates the interactions between members, which need to be neutralized by an appropriate coordination plan. This paper proposes an analytical scenario-based coordination model that resolves channel conflicts and pays dividends to the involving members through augmenting their social, economic, and environmental performance. We show that the coordination plan could be a practical policy to increase the system’s adaptability to disruption. Under the coordinated model, by increasing a retailer’s collection disruption, the other one invests more in CSR efforts to compensate for its competitor’s lower collection, preventing loss for the whole channel. We also demonstrate that the proposed model maintains the chain’s balance and prevents loss in case of a highly competitive CSR-based collection and boosts the collection amount, market demand, and the whole chain’s profitability simultaneously.

现实世界中的不确定性会干扰操作，包括闭环供应链（CLSC）中的收集过程。在制药行业，由于制药残留物含有威胁环境和人类健康的化学物质，对收集的破坏更为严重。本文围绕一个实际的制药案例所面临的挑战，该案例通过闭环系统设计来实现循环经济原则，考虑到可持续性问题，并寻求有效管理收集中断的方法。该案例包括一家制造商，该公司投资于绿色研发（R＆D），以及两家零售商在企业社会责任（CSR）努力上竞争，以提高回收量和市场需求。这种竞争环境会引起利益冲突，并使成员之间的互动变得复杂，需要通过适当的协调计划来消除这种互动。本文提出了一种基于情景分析的协调模型，该模型可以解决渠道冲突，并通过提高成员的社会，经济和环境绩效向参与成员分配利益。我们表明，协调计划可能是增加系统对中断的适应性的实用政策。在协调模式下，另一方通过增加零售商的收款中断，来加大对企业社会责任的投入，以弥补其竞争对手较低的收款额，从而防止整个渠道的损失。