Abstract Developing environmental and cost-effective antifouling technologies is essential to solve serious biofouling problems. Recently, enzyme mimics and halogenating enzymes have caught progressively attention as valuable tools to combat biofilm formation. In this work, the core-shell structure of CeO2@C, as one effective haloperoxidase-like enzyme mimics, was successfully synthesized using the carbon sphere as template through a simple coprecipitation method. Through the UV–vis absorption spectra and kinetic measurements, the CeO2@C displays intrinsic haloperoxidase-like activity via catalyzing the bromination of organic signaling compounds. Meanwhile, the prepared CeO2@C catalyst process high catalytic stability and recyclability, corresponding to a well catalytic performance repeatability after refresh of raw substrates (at least 10 times). The antibactrial property of CeO2@C as haloperoxidase mimicry is evaluated by immersing titanium plate/CeO2@C modified titanium plates into bacterial suspensions with different conditions for 4 h at 37 °C. It can catalyze the oxidation of Br− with H2O2 to the corresponding hypobromous acid (HBrO), which exhibits strong antibacterial activity against Gram-negative (Escherichia coli), Gram-positive (Staphylococcus aureus) bacteria and typical marine (Pseudomonas aeruginosa) bacteria. This study introduces a stable, non-poisonous and inexpensive biomimetic material for antibacterial, antifouling and disinfection applications based on novel sustainable and conservation methods.

中文翻译：

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研究纳米核壳 CeO2@C 作为卤代过氧化物酶模拟催化剂用于防污应用的特性

摘要 开发环保且具有成本效益的防污技术对于解决严重的生物污损问题至关重要。最近，酶模拟物和卤化酶作为对抗生物膜形成的宝贵工具越来越受到关注。在这项工作中，以碳球为模板，通过简单的共沉淀方法成功合成了 CeO2@C 的核壳结构，作为一种有效的类卤过氧化物酶模拟物。通过紫外可见吸收光谱和动力学测量，CeO2@C 通过催化有机信号化合物的溴化显示出固有的类卤代过氧化物酶活性。同时，制备的CeO2@C催化剂具有较高的催化稳定性和可回收性，对应于原始基材刷新后（至少10次）良好的催化性能重复性。CeO2@C 作为卤代过氧化物酶模拟物的抗菌性能是通过将钛板/CeO2@C 改性钛板浸入不同条件的细菌悬浮液中，在 37°C 下浸泡 4 小时来评估的。它可以催化 Br− 与 H2O2 氧化成相应的次溴酸 (HBrO)，对革兰氏阴性 (大肠杆菌)、革兰氏阳性 (金黄色葡萄球菌) 细菌和典型的海洋 (铜绿假单胞菌) 细菌表现出很强的抗菌活性。本研究基于新颖的可持续和保护方法，引入了一种稳定、无毒且廉价的仿生材料，用于抗菌、防污和消毒应用。