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Recent advances in the synthesis of heterocycles and pharmaceuticals from the photo/electrochemical fixation of carbon dioxide
Chemical Engineering Science ( IF 4.1 ) Pub Date : 2021-01-01 , DOI: 10.1016/j.ces.2020.116142
Hoang Long Ngo , Dinesh Kumar Mishra , Vivek Mishra , Cong Chien Truong

Abstract In recent years, the deployment of carbon dioxide (CO2) as a renewable and benign building block in the assembly of bioactive heterocycles and pharmaceuticals has become one of the most appealing topics in the CO2 utilization. In this context, the photo/electrochemical approaches are acknowledged as powerful toolkits in the manufacture of CO2-based heterocycles and pharmaceuticals, which enables the CO2 valorization to take place in a more mild-mannered and eco-friendly conditions with respect to other chemical patterns. In this review, several typical examples on the photo/electrochemical fixation of CO2 into divergent heterocyclic scaffolds and important pharmaceuticals are highlighted. Furthermore, the detailed mechanistic descriptions of various synthetic paradigms are also described to provide a better understanding on the success of these strategies.

中文翻译:

二氧化碳的光/电化学固定合成杂环化合物和药物的最新进展

摘要 近年来,在生物活性杂环化合物和药物的组装中,将二氧化碳 (CO2) 作为一种可再生的良性构建块进行部署已成为 CO2 利用中最具吸引力的话题之一。在这种情况下,光/电化学方法被认为是制造基于 CO2 的杂环化合物和药物的强大工具包,这使得 CO2 的价值化能够在比其他化学模式更温和、更环保的条件下进行. 在这篇综述中,重点介绍了将 CO2 光/电化学固定成不同杂环支架和重要药物的几个典型例子。此外,
更新日期:2021-01-01
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