Poxytrins (Pufa Oxygenated Trienes), are dihydroxy derivatives from polyunsaturated fatty acids (PUFA) with adjacent hydroxyl groups to a conjugated triene having the specific E,Z,E geometry. They are made by the double action of one lipoxygenase or the combined actions of two lipoxygenases, followed by reduction of the resulting hydroperoxides by with glutathione peroxidase. Because of their E,Z,E conjugated triene, poxytrins may inhibit inflammation associated with cyclooxygenase (COX) activities, and reactive oxygen species (ROS) formation. In addition of inhibiting COX activities, at least one poxytrin, namely protectin DX (PDX) from docosahexaenoic acid (DHA), has also been reported as able to inhibit influenza virus replication by targeting its RNA metabolism.

氧三环（Pufa氧化三烯）是具有相邻羟基的多不饱和脂肪酸（PUFA）形成具有特定E，Z，E几何形状的共轭三烯的二羟基衍生物。它们是通过一种脂氧合酶的双重作用或两种脂氧合酶的联合作用，然后用谷胱甘肽过氧化物酶还原所得的氢过氧化物来制备的。由于它们的E，Z，E共轭三烯，氧合环素可以抑制与环氧合酶（COX）活性和活性氧（ROS）形成有关的炎症。除了抑制COX活性外，还报道了至少一种Poxytrin，即二十二碳六烯酸（DHA）的保护素DX（PDX），可以通过靶向其RNA代谢来抑制流感病毒复制。