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Comparative evaluation of the antioxidant activity of some ortho-substituted mono- and dialkylphenols with the para-positioned hydroxymethyl group
Russian Chemical Bulletin ( IF 1.7 ) Pub Date : 2020-08-01 , DOI: 10.1007/s11172-020-2937-x
E. V. Buravlev , I. V. Fedorova , O. G. Shevchenko , A. V. Kutchin

The para-hydroxymethyl derivatives of 2,6-di-tert-butylphenol, 2,6-diisobornylphenol, 2-isobornyl-6-tert-butylphenol, 2-isobornyl-6-methylphenol, and 2-isobornylphenol were synthesized. A comparative evaluation of the antioxidant properties of the synthesized compounds was carried out in in vitro models. The activity of derivatives is predetermined by the number and bulkiness of the substituents at the ortho positions relative to the phenolic OH group and is consistent with the relationships previously identified by us for other phenolic antioxidants.

中文翻译:

一些具有对位羟甲基的邻位取代的单烷基酚和二烷基酚的抗氧化活性的比较评价

合成了2,6-二叔丁基苯酚、2,6-二异冰片基苯酚、2-异冰片基-6-叔丁基苯酚、2-异冰片基-6-甲基苯酚和2-异冰片基苯酚的对羟甲基衍生物。在体外模型中对合成化合物的抗氧化性能进行了比较评估。衍生物的活性由相对于酚羟基的邻位取代基的数量和体积预先确定,并且与我们之前确定的其他酚类抗氧化剂的关系一致。
更新日期:2020-08-01
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