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Role of CT in differentiation between subtypes of lung cancer; is it possible?
The Egyptian Journal of Bronchology ( IF 1.0 ) Pub Date : 2020-09-17 , DOI: 10.1186/s43168-020-00027-w
Heba Said Gharraf , Sayed Mohamed Mehana , Mostafa Ali ElNagar

Context and purpose: lung cancer is the second in the incidence rate and the first in death rate in the United States of America in 2017. Its treatment depends upon the tumor staging as well as the histological subtype of lung cancer. CT has been the modality of choice for screening as well as diagnosis of lung cancer; however, few studies tried to correlate different CT features of lung cancer to certain pathological subtypes. Our study aims to assess the CT characteristics of the subtypes of bronchogenic carcinoma. SQCC shows a higher incidence of central location compared with the rest of the lung cancers (significance level of 50%, p value of 0.5), internal cavitations (significance level of 94.9%, p value of less than 0.05) as well as more frequency of higher stage within the study population, ADC shows significant predilection to peripheral location compared with the rest of the lung cancers (significance level of 94.9%, p value of less than 0.05). There is an evident correlation between the MDCT diagnosis of bronchogenic carcinoma and that of histopathology/cytology. The most common types are SQCC and ADC subtypes. The SQCC type of bronchial carcinoma tends to be central with the internal cavitations are common while ADC tends to be peripheral and solid.

中文翻译:

CT在肺癌亚型分化中的作用;可能吗?

背景与目的:2017年,肺癌在美国的发病率中排名第二,在死亡率中排名第一。其治疗取决于肿瘤的分期以及肺癌的组织学亚型。CT已经成为肺癌筛查和诊断的首选方式。但是,很少有研究试图将肺癌的不同CT特征与某些病理亚型相关联。我们的研究旨在评估支气管癌亚型的CT特征。与其他肺癌(显着性水平为50%,p值为0.5),内部空化(显着性水平为94.9%,p值小于0.05)相比,SQCC显示出中心位置发生率更高在研究人群中处于较高阶段 与其他肺癌相比,ADC显示出对周围位置的明显偏爱(显着性水平为94.9%,p值小于0.05)。支气管癌的MDCT诊断与组织病理学/细胞学诊断之间存在明显的相关性。最常见的类型是SQCC和ADC子类型。SQCC型支气管癌倾向于以中央为中心,内部空洞很常见,而ADC则倾向于外围和实体。
更新日期:2020-09-18
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