An enantiomer of nabscessin A (1), an aminocyclitol amide with antimicrobial activity, was synthesized from myo-inositol and dimethyl d-camphor acetal in 14 steps. Formal synthesis of natural nabscessin A was also achieved through the new approach to access both enantiomers of 4,5-di-O-benzyl-myo-inositol, derived from the same set of starting materials. This synthesis features utilizations of the existing framework of myo-inositol and a regioselective esterification.

中文翻译：

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从肌醇和D-樟脑不对称合成纳豆素A。

nabscessin A的对映体（1），一个氨基环醇酰胺具有抗微生物活性，由合成肌醇肌醇和二甲基d -樟脑缩醛在14个步骤。还可以通过新方法来获得天然那巴豆素A的形式合成，该新方法可访问衍生自同一组起始原料的4,5-二-O-苄基-肌醇肌醇的两种对映体。该合成的特征在于利用了肌醇的现有构架和区域选择性酯化。