The use of organic solvents for the preparation of nanofibers are challenged due to their volatile and hazardous behavior. Recently deep eutectic solvents (DES) are widely recognized as non-volatile and non-hazardous solvents which never been utilized directly for nanofabrication via electrospinning. Here, we present the preparation of Zein nanofibers using deep eutectic solvents (DES-Zein). The DES-Zein nanofibers were produced at an optimized polymer concentration of 45% (w/w) with pH 7.3 and electroconductivity 233 mS cm⁻¹. DES-Zein nanofibers showed aligned to tweed like cedar leaf morphology tuned by varying the spreading angle from 0° to 90°. In contrast to hydrophobic conventional Zein nanofibers, DES-Zein nanofibers showed super hydrophilic character and about 200 nm finer average diameter. The proposed method of preparing Zein nanofibers using DES opens a new door to continuous electrospinning with tunable morphology, having potential to be used for environmental and biomedical applications.

使用有机溶剂制备纳米纤维由于其挥发性和危险行为而受到挑战。最近，低共熔溶剂（DES）被广泛认为是非挥发性且无害的溶剂，从未通过静电纺丝直接用于纳米制造。在这里，我们介绍了使用低共熔溶剂（DES-Zein）制备玉米醇溶蛋白纳米纤维。 DES-玉米醇溶蛋白纳米纤维是在优化的聚合物浓度为45%（w/w）、pH 7.3和电导率233 mS cm ^-1下生产的。 DES-玉米醇溶蛋白纳米纤维显示出与花呢类似的雪松叶形态，通过将铺展角度从 0° 改变到 90° 进行调整。与疏水性传统玉米醇溶蛋白纳米纤维相比，DES-玉米醇溶蛋白纳米纤维表现出超亲水特性和约200 nm的细平均直径。所提出的使用 DES 制备玉米醇溶蛋白纳米纤维的方法为具有可调形态的连续静电纺丝打开了新的大门，具有用于环境和生物医学应用的潜力。