ABSTRACT

Background

Atopic dermatitis is a chronic inflammatory skin disease that has substantial effects on patients’ quality of life, with a prevalence between 2.2% and 17.6% worldwide. This study aimed to evaluate the use of specialized care resources generated by children and adults with atopic dermatitis, and the associated direct medical costs.

Methods

Admission details from patients admitted in specialized healthcare centers (inpatient and outpatient care) in Spain between 1 January 2000 and 31 December 2017 were analyzed in a retrospective multicentre study.

Results

Records corresponded to 3036 patients, 1266 aged 5 years or younger. Comorbid conditions corresponded to skin infections and respiratory difficulties (asthma, bronchiectasis). Hospital incidence of atopic dermatitis was 5.8 per 100,000 persons, stable over the study period, and 30.0 per 100,000 in those aged 5 years and younger. Mean annual direct medical cost per patient was €2469. Overall, direct medical costs per patient increased significantly over the study period (p < 0.0001).

Conclusion

Hospital incidence of atopic dermatitis remained stable over the study period, which is in contrast with the increasing incidence reported by the Spanish government in primary care centers. The increase in direct medical costs of specialized care responded to the increase in treatment costs.

中文翻译：

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西班牙专业中心的特应性皮炎：发病率和成本的回顾性分析（2000-2017）

摘要

背景

特应性皮炎是一种慢性炎症性皮肤病，对患者的生活质量有重大影响，全球患病率为 2.2% 至 17.6%。本研究旨在评估特应性皮炎儿童和成人产生的专业护理资源的使用情况，以及相关的直接医疗费用。

方法

一项回顾性多中心研究分析了 2000 年 1 月 1 日至 2017 年 12 月 31 日期间在西班牙专业医疗中心（住院和门诊治疗）住院的患者的入院细节。

结果

记录对应于 3036 名患者，其中 1266 名年龄在 5 岁或以下。合并症对应于皮肤感染和呼吸困难（哮喘、支气管扩张）。特应性皮炎的住院发病率为每 100,000 人 5.8 人，在研究期间稳定，5 岁及以下人群中为每 100,000 人 30.0。每位患者的年平均直接医疗费用为 2469 欧元。总体而言，每位患者的直接医疗费用在研究期间显着增加（p < 0.0001）。

结论

在研究期间，特应性皮炎的医院发病率保持稳定，这与西班牙政府在初级保健中心报告的发病率不断增加形成鲜明对比。专科护理的直接医疗费用的增加与治疗费用的增加有关。