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Simultaneous determination of multiple active 2‐(2‐phenylethyl)chromone analogues in agarwood by HPLC, QAMS, and UPLC‐MS
Phytochemical Analysis ( IF 3.0 ) Pub Date : 2020-09-16 , DOI: 10.1002/pca.2989
Mei Gao 1 , Xiaomin Han 2 , Junqing Huang 3 , Ying Sun 1 , Yangyang Liu 4 , Hongjiang Chen 5 , Yue Jin 1 , Yun Yang 4 , Zhihui Gao 1 , Yanhong Xu 1 , Zheng Zhang 1 , Chunnian He 1
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Chromones are the major constituents of agarwood and are considered to be directly related to its quality. Agarotetrol, a chromone derivative, is a Chinese Pharmacopoeia content detection index. However, comprehensive high‐performance liquid chromatography (HPLC), quantitative analysis of multiple components by a single marker (QAMS), and ultra‐performance liquid chromatography mass spectrometry (UPLC‐MS) analyses of this pharmacopeial plant material have never been performed. Moreover, reports regarding the separation and detection of multiple active 2‐(2‐phenylethyl)chromone analogues from this plant material are surprisingly scarce.
更新日期:2020-09-16
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