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Hypoxia inducible factor‐2α importance for migration, proliferation, and self‐renewal of trunk neural crest cells
Developmental Dynamics ( IF 2.5 ) Pub Date : 2020-09-17 , DOI: 10.1002/dvdy.253
Camilla U Niklasson 1 , Elina Fredlund 1, 2 , Emanuela Monni 3, 4 , Jessica M Lindvall 5 , Zaal Kokaia 3, 4 , Emma U Hammarlund 1 , Marianne E Bronner 6 , Sofie Mohlin 1, 2, 6
Affiliation  

The neural crest is a transient embryonic stem cell population. Hypoxia inducible factor (HIF)‐2α is associated with neural crest stem cell appearance and aggressiveness in tumors. However, little is known about its role in normal neural crest development.

中文翻译:

缺氧诱导因子-2α对躯干神经嵴细胞迁移、增殖和自我更新的重要性

神经嵴是一个短暂的胚胎干细胞群。缺氧诱导因子 (HIF)-2α 与神经嵴干细胞的出现和肿瘤的侵袭性有关。然而,对其在正常神经嵴发育中的作用知之甚少。
更新日期:2020-09-17
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