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Non-pharmacologic management of orthostatic hypotension
Autonomic Neuroscience ( IF 3.2 ) Pub Date : 2020-12-01 , DOI: 10.1016/j.autneu.2020.102732
Gisela Chelimsky 1 , Thomas Chelimsky 2
Affiliation  

Orthostatic hypotension (OH), a debilitating disorder characterized by a drop in blood pressure when in the upright position, may be treated through several pharmacologic and lifestyle modifications. The treatment is aimed at decreasing the symptoms, mainly the falls, increase the standing time, and improve the activities of daily life. A recent expert consensus outlined the management of orthostatic hypotension and included 4 sequential steps: 1) review medications and modify or remove those that may aggravate or cause OH; 2) non-pharmacologic measures; 3) pharmacologic measures and 4) treatment combinations. The aim of this manuscript is to review the non-pharmacological approach. In milder cases, this approach may suffice, but with more severe symptoms, such as falls, syncope or near-syncope, a pharmacological strategy is simultaneously employed. Furthermore, most non-pharmacological measures are combined. The non-pharmacological approach is aimed at optimizing blood volume, decreasing postural venous pooling, reducing heat and post-prandial induced vasodilation, emphasizing physical conditioning, and minimizing nocturnal diuresis.

中文翻译:

体位性低血压的非药物治疗

直立性低血压 (OH) 是一种以直立时血压下降为特征的衰弱性疾病,可以通过多种药物和生活方式的改变来治疗。治疗旨在减轻症状,主要是跌倒,增加站立时间,改善日常生活活动。最近的专家共识概述了体位性低血压的管理,包括 4 个连续步骤:1) 审查药物并修改或去除可能加重或导致 OH 的药物;2) 非药物措施;3) 药理措施和 4) 治疗组合。这份手稿的目的是审查非药物方法。在较轻的情况下,这种方法可能就足够了,但对于更严重的症状,例如跌倒、晕厥或接近晕厥,同时采用药理学策略。此外,结合了大多数非药物措施。非药物方法旨在优化血容量、减少体位静脉淤积、减少热量和餐后引起的血管舒张、强调身体状况并尽量减少夜间利尿。
更新日期:2020-12-01
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