In our continuous search for bioactive natural products from marine zoantharians, three serotonin derivatives 1-3 and one dopamine analogue 4 together with the known ecdysteroids ajugasterone C (5) and turkesterone (6) and zoanthoxanthin derivative 3-norpseudozoanthoxanthin (7) were isolated from Zoanthus cf. sansibaricus collected off the coast of Papua New Guinea. The structures of these alkaloids were elucidated through spectroscopic analyses including 1D and 2D NMR experiments and HRESIMS data. This is the first report of serotonin and dopamine derived alkaloids from species of the genus Zoanthus. Compounds 1-3 demonstrated moderate bactericidal activity against S. aureus NCTC 7447 with an IC₅₀ value of 83.3, 41.9 and 37.4 μM.

在我们的连续搜索生物活性天然产物从海洋zoantharians，三羟色胺衍生物1 - 3和一个多巴胺类似物4与已知的蜕皮类固醇ajugasterone C（一起5）和turkesterone（6）和zoanthoxanthin衍生物3- norpseudozoanthoxanthin（7）从分离Zoanthus参见。sansibaricus收集了巴布亚新几内亚沿海地区。通过包括1D和2D NMR实验以及HRESIMS数据在内的光谱分析阐明了这些生物碱的结构。这是来自Zoanthus属物种的血清素和多巴胺衍生生物碱的首次报道。化合物1 - 3表现出对温和的杀菌活性的金黄色葡萄球菌NCTC 7447与IC ₅₀ 83.3，41.9和37.4μM的值。