Abstract Ytterbium (Yb) containing magnesium alloys have aroused extensive interests because of their excellent mechanical properties. Unfortunately, their potential biomedical applications as a biodegradable implant material remain uncertain to date. In this study, in vitro degradation behavior and biocompatibility of the newly developed Mg–5.8 Zn–2.0 Yb–0.5 Zr (wt.%, denoted as ZYbK620) alloy during aging treatment were investigated. The results reveal that the dimension and distribution of Yb containing phases act a significant role in biocorrosion resistance and biocompatibility of ZYbK620 alloys. The peak-aged sample with much finer and denser nanoprecipitates possesses the lowest corrosion rate and best integrity after long-term immersion. Further biocompatibility testing demonstrates that the alloys with different aging times all exhibit favorable cytocompatibility and hemocompatibility, suggesting that the ZYbK620 alloy can be a promising candidate for biomedical applications.

中文翻译：

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Mg-5.8 Zn-2.0 Yb-0.5 Zr合金在时效处理过程中的体外降解行为和生物相容性

摘要 含镱（Yb）镁合金由于其优异的力学性能引起了广泛的关注。不幸的是，它们作为可生物降解的植入材料的潜在生物医学应用至今仍不确定。在这项研究中，研究了新开发的 Mg-5.8 Zn-2.0 Yb-0.5 Zr（wt.%，表示为 ZYbK620）合金在时效处理过程中的体外降解行为和生物相容性。结果表明，含 Yb 相的尺寸和分布对 ZYbK620 合金的抗生物腐蚀性和生物相容性起着重要作用。具有更细更密的纳米沉淀物的峰值老化样品在长期浸泡后具有最低的腐蚀速率和最佳的完整性。