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Detrimental Effects of Bisphenol Compounds on Physiology and Reproduction in Fish: A Literature Review.
Environmental Toxicology and Pharmacology ( IF 4.3 ) Pub Date : 2020-09-17 , DOI: 10.1016/j.etap.2020.103497
Mehwish Faheem 1 , Ramji Kumar Bhandari 2
Affiliation  

Bisphenol-A is one of the most studied endocrine-chemicals, which is widely used all over the world in plastic manufacture. Because of its extensive use, it has become one of the most abundant chemical environmental pollutants, especially in aquatic environments. BPA is known to affect fish reproduction via estrogen receptors but many studies advocate that BPA affects almost all aspects of fish physiology. The possible modes of action include genomic, as well as and non-genomic mechanisms, estrogen, androgen, and thyroid receptor-mediated effects. Due to the high detrimental effects of BPA, various analogs of BPA are being used as alternatives. Recent evidence suggests that the analogs of BPA have similar modes of action, with accompanying effects on fish physiology and reproduction. In this review, a detailed comparison of effects produced by BPA and analogs and their mode of action is discussed.



中文翻译:

双酚化合物对鱼类生理和繁殖的不利影响:文献综述。

双酚 A 是研究最多的内分泌化学物质之一,在世界各地广泛用于塑料制造。由于其广泛使用,它已成为最丰富的化学环境污染物之一,尤其是在水生环境中。众所周知,BPA 通过雌激素受体影响鱼类繁殖,但许多研究主张 BPA 几乎影响鱼类生理的所有方面。可能的作用方式包括基因组以及非基因组机制、雌激素、雄激素和甲状腺受体介导的作用。由于 BPA 的高度有害影响,BPA 的各种类似物被用作替代品。最近的证据表明,BPA 的类似物具有相似的作用方式,并伴随着对鱼类生理和繁殖的影响。在本次审查中,

更新日期:2020-11-12
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