Enhancers switch genes on and off in response to a variety of intrinsic and external cellular signals. They are the cornerstone of gene regulation and the most pervasive constituents of the regulatory genome. Sequence polymorphisms in enhancer DNAs are a major source of population diversity and predilection to disease. To view this SnapShot, open or download the PDF.

中文翻译：

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快照：监管基因组。

增强子响应各种内在和外在的细胞信号打开和​​关闭基因。它们是基因调控的基石，也是调控基因组中最普遍的成分。增强子 DNA 中的序列多态性是种群多样性和疾病易感性的主要来源。要查看此快照，请打开或下载 PDF。