Screening leads to meaningful reductions in deaths from cancers. However, reductions in all-cause mortality (ACM) are harder to demonstrate. Failure to demonstrate ACM benefit should not diminish advances in cancer screening. We consider how co-morbidities related to an aging and damaged soma can hinder achievement of ACM benefit.

中文翻译：

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癌症筛查、生存替代物和体细胞。

筛查可以显着减少癌症死亡人数。然而，全因死亡率 (ACM) 的降低更难证明。未能证明 ACM 的益处不应削弱癌症筛查的进步。我们考虑与衰老和受损躯体相关的合并症如何阻碍 ACM 益处的实现。