Abstract A phytochemical investigation on the twigs and leaves of Kopsia hainanensis Tsiang resulted in the isolation and identification of 18 alkaloids, including two sarpagine type alkaloids (1 and 2), five eburnane type alkaloids (3–7), three aspidofractinine type alkaloids (8–10), one vincadine type alkaloid (11), three akuammiline type alkaloids (12–13 and 15), one corynanthean type alkaloid (14), two ajmalicine-like type alkaloids (16 and 17), and one aspidospermine type alkaloid (18). The new structure of compound 1 was elucidated by means of spectroscopic analysis, including HRESIMS, and 1D and 2D NMR experiments. Compounds 1–2, 4–5, 7, and 10–17 are herein reported for the first time from this plant, while the compounds 1, 2, 7, and 12–17 have not been previously recorded in the Kopsia genus. The chemotaxonomic significance and distribution of these monoterpenoid indole alkaloids in Kopsia genus are discussed.

中文翻译：

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海南红豆杉单萜吲哚生物碱

摘要 对海南红豆杉的枝叶进行植物化学研究，分离鉴定了 18 种生物碱，包括两种沙巴金型生物碱（1 和 2）、五种丁烷型生物碱（3-7）、三种 aspidofractinine 型生物碱（8 –10)、1 种长春卡丁型生物碱 (11)、3 种 akuammiline 型生物碱 (12-13 和 15)、1 种珊瑚藻类生物碱 (14)、2 种类阿马利辛型生物碱 (16 和 17) 和 1 种天冬酰胺型生物碱 ( 18）。通过光谱分析，包括HRESIMS、一维和二维核磁共振实验，阐明了化合物1的新结构。化合物 1-2、4-5、7 和 10-17 是本文首次报道的来自该植物的化合物，而化合物 1、2、7 和 12-17 此前未在 Kopsia 属中记录。