The aim of this study was to evaluate the effectiveness of OLIF (oblique lumbar interbody fusion) in the treatment of lumbar degenerative spondylolisthesis with sagittal imbalance. Fifty-nine patients were included in our analysis. Included patients were divided into 2 groups according to the surgical techniques: PLIF (posterior lumbar interbody fusion) (n = 31) and OLIF + PSF (OLIF combined with posterior spinal fixation) (n = 28). Perioperative radiographic parameters, complications, and clinical outcome from each group were assessed and compared. The operation time for both groups was 165.1 min in the OLIF group and 182.1 min in the PLIF group (P < 0.05). The intraoperative blood loss was 190.6 ml in the OLIF group and 356.3 ml in the PLIF group (P < 0.05). The number of intraoperative and postoperative complications for both groups was 7 in the OLIF group and 11 in the PLIF group. Significant clinical improvement was observed in VAS scores and ODI when comparing preoperative evaluation and final follow-up. The preoperative SVA (the distance from the posterosuperior corner of S1body to the C7 plumb line), PI (pelvic incidence), LL (lumbar lordosis), PI-LL mismatch, DH (disc height), and lumbar Cobb angles of both groups were similar. The postoperative and final follow-up SVA, LL, PI-LL mismatch, and disc height were improved in both groups, and a statistical difference was found between both groups (P < 0.05). An improvement of SVA, LL, PI-LL mismatch, and disc height at the OLIF group was better than that found at the PLIF group. An improvement in radiographic and clinical outcomes for the OLIF group was better than that seen for the PLIF group. Then, OLIF had a more curative effect in lumbar degenerative spondylolisthesis with sagittal imbalance.

本研究的目的是评估OLIF（斜腰椎间融合术）在治疗腰椎退行性滑脱伴矢状面失衡中的有效性。59 名患者被纳入我们的分析。纳入的患者根据手术技术分为两组：PLIF（后路腰椎椎间融合术）（n =31）和OLIF+PSF（OLIF联合后路脊柱固定术）（n =28）。评估并比较了每组的围手术期影像学参数、并发症和临床结果。两组手术时间OLIF组165.1 min，PLIF组182.1 min（P< 0.05)。OLIF组术中失血量为190.6 ml，PLIF组为356.3 ml（P < 0.05）。两组术中术后并发症发生数均为OLIF组7例，PLIF组11例。在比较术前评估和最终随访时，观察到 VAS 评分和 ODI 的显着临床改善。两组术前SVA（S1body后上角至C7铅垂线的距离）、PI（骨盆入射角）、LL（腰椎前凸）、PI-LL失配、DH（椎间盘高度）、腰椎Cobb角分别为相似的。两组术后及末次随访SVA、LL、PI-LL错配、椎间盘高度均有改善，两组间差异有统计学意义（P< 0.05)。OLIF 组 SVA、LL、PI-LL 不匹配和椎间盘高度的改善优于 PLIF 组。OLIF 组的影像学和临床结果的改善优于 PLIF 组。然后，OLIF对腰椎退行性滑脱伴矢状面失衡的疗效更佳。